The thyroid peroxidase (TPO) antibodies test is a blood test that measures the level of antibodies that target the thyroid peroxidase enzyme. TPO is an enzyme that plays a key role in the production of thyroid hormones. Elevated levels of TPO antibodies can indicate an autoimmune thyroid condition, such as Hashimoto's thyroiditis or Graves' disease.
This test is often used to help diagnose thyroid disorders and monitor the effectiveness of treatment. It may be ordered if a healthcare provider suspects that a patient's symptoms, such as fatigue, weight gain, hair loss, or changes in mood, are due to a thyroid disorder. It may also be ordered to assess the risk of developing a thyroid disorder, especially in individuals with a family history of thyroid problems.
Elevated levels of TPO antibodies in the blood may indicate that the immune system is attacking the thyroid gland, leading to inflammation and dysfunction. Treatment for thyroid disorders typically involves hormone replacement therapy or medications to suppress the immune response.
It is important to discuss the results of the TPO antibodies test with a healthcare provider to determine the appropriate course of action. Additional tests, such as thyroid hormone levels and imaging studies, may be needed to confirm a diagnosis and develop a treatment plan.
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